Living cells in a dish under the microscope (by Daniela AD Costa)
Project title: Novel Biomaterial-based Device for the Treatment of Progressive MS. An Integrated Pan-European Approach
Overview of our Programme
PMSMatTrain focuses on gaining a comprehensive understanding of the progressive phase of multiple sclerosis (PMS) from basics to translation, fully supported by eight beneficiaries (six research institutions and two SMEs).
Progressive Multiple Sclerosis (PMS)
Currently, systemic delivery of drugs for PMS is limited by the inability of drugs to cross the blood-brain barrier (BBB). The PMSMatTrain project will develop new technology that allows controlled and targeted delivery of therapeutic molecules directly to the brain cortical tissue, exploiting “tuneable” biomaterials that allow a multi-phasic delivery of therapeutics from a minimally-invasive implantable device in the skull. Aimed specifically at generating drug regimes for treatment of the later progressive phases of MS, cocktails of anti-inflammatory agents and ...
Training of our Researchers
The recruited fellows (or so-called early-stage researchers ESRs) will receive compulsory discipline-specific, generic and complementary training. The PMSMatTrain’s Joint Research Education and Training programme provides high-quality research and transferable skills training in intellectual property, leadership skills, innovation, regulatory affairs, gender policy, and medical device evaluation.
This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No 813263.